Intervention 3: maintenance: 0.5% halothane (N = 20) Intervention 2: maintenance: 1 % isoflurane (N = 20) Intervention 1: maintenance: 0.5% isoflurane (N = 20) Procedure: caesarean delivery ('elective primary or repeat, or arrest of dilatation') Quote: 'All patients were interviewed 24 h postвЂђpartum to determine the incidence of awareness by a person who was unaware of the anesthetic management of the mother'Д¬omment: awareness outcome part of inclusion criteria Random sequence generation (selection bias)Д«linding of participants and personnel (performance bias)Д«linding of outcome assessment (detection bias) Method of outcome determination: interviewД®mail sent 3 November 2010 as with most RCTs that were published years ago, it was difficult to find current contact information for most authors Time of outcome determination: 24 h post partum No titration anaesthetic strategy for light anaesthesia defined in the paperД¬omment: no sample size calculation (power analysis) provided in paper NonвЂђrandomized portion of anaesthetic: parts of potent inhalational technique (volatile agent)/N 2O yes/hypnotic/supplemental narcotics/muscle relaxants induction yes/maintenance unclearДЄnaesthesia induction: 4 mg/kg thiopental + succinylcholine 1.5 mg/kg + curare 3 mg anaesthesia maintenance after delivery: N 2O + narcotics

Quote: 'Of the patients who had N 2O alone, 12.5% (2/16) had awareness versus none in the other groups' Secondary outcome: awareness/wakefulness as defined using an awareness classification system (see Table 1): class 4 Primary outcomes: Quote: 'adverse neonatal effects of sub anesthetic doses of halothane or enflurane.'

Intervention 5: maintenance: general anaesthesia 1.0% enflurane + 50% N 2O (N = 13) Intervention 4: maintenance: general anaesthesia 0.5% enflurane + 50% N 2O (N = 18) Intervention 3: maintenance: general anaesthesia 0.5% halothane + 50% N 2O (N = 18) Intervention 2: maintenance: general anaesthesia 0.25% halothane + 50% N 2O (N = 16) Intervention 1: maintenance: general anaesthesia 50% N 2O (N = 16): control Randomized portion of anaesthetic: volatile agent doses Procedure: caesarean delivery ('elective')

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